With two outs in the bottom of the ninth inning, Hanley Ramirez grounded into a fielder’s choice, sealing Manaea’s no-hit bid and a 3-0 Oakland win. It’s the first time Boston has been no-hit since April 22, 1993, and the first no-no thrown by an A’s pitcher since Dallas Braden’s perfect game in 2010.

Manaea, 26, completed the feat in a tidy 136 minutes. He struck out 10 batters, walking two, on 108 pitches (75 strikes).

The Red Sox were an unlikely victim; their 25-year stretch without being no-hit served as the second-longest active streak in MLB. Boston owns baseball’s best record and had gone for at least 10 hits in each of its last seven games. They lead MLB in runs (123) and run differential (plus-70).

Manaea, a former top prospect, is off to the best start in three big league seasons. He’s 3-2 with a 1.32 ERA and 30 strikeouts across 36 2/3 innings after Saturday, the 58th start of his career.